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Evaluation Potency And Activity

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  • Discovery and development of renin inhibitors — Renin inhibitors are antihypertensive drugs that inhibit the first and rate limiting step of the renin angiotensin aldosterone system (RAAS). Since the 1970s scientists have been trying to develop potent inhibitors with acceptable oral… …   Wikipedia

  • Discovery and development of TRPV1 antagonists — Chronic pain remains a recognized unmet medical need. Consequently, the search for new analgesic agents is being intensively studied by the pharmaceutical industry. The TRPV1 receptor is an ion channel that has been implicated in mediation of… …   Wikipedia

  • Discovery and development of cyclooxygenase 2 inhibitors — Cyclooxygenases are enzymes that take part in a complex biosynthetic cascade that results in the conversion of polyunsaturated fatty acids to prostaglandins and thromboxane(s).[1] Their main role is to catalyze the transformation of arachidonic… …   Wikipedia

  • Discovery and development of dual serotonin and norepinephrine reuptake inhibitors — Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs used in the treatment of major depressive disorder (MDD). SNRIs are potent inhibitors of serotonin (5 Hydroxytryptamine, 5 HT) and norepinephrine (NE,… …   Wikipedia

  • Health and Disease — ▪ 2009 Introduction Food and Drug Safety.       In 2008 the contamination of infant formula and related dairy products with melamine in China led to widespread health problems in children, including urinary problems and possible renal tube… …   Universalium

  • Semantic differential — Diagnostics Fig. 1. Modern Japanese version of the Semantic Differential. The Kanji characters in background stand for God and Wind respectively, with the compound reading Kamikaze . (Adapted from Dimensions of Meaning. Visual Statistics… …   Wikipedia

  • Discovery and development of non-nucleoside reverse-transcriptase inhibitors — Non nucleoside reverse transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic… …   Wikipedia

  • Affect control theory — In control theory (sociology) Affect control theory proposes that individuals maintain affective meanings through their actions and interpretations of events. The activity of social institutions occurs through maintenance of culturally based… …   Wikipedia

  • Dioxins and dioxin-like compounds — (DLC)[1] are by products of various industrial processes, and are commonly regarded as highly toxic compounds that are environmental pollutants and persistent organic pollutants (POPs).[2] They include:[1][3] Polychlorinated dibenzo p dioxins… …   Wikipedia

  • semantic differential — A method devised by C. E. Osgood and his colleagues to study the connotative meaning of cultural objects, using a set of bipolar rating scales (for example sweet/sour, good/bad), in order to elicit data (see, and , The Measurement of Meaning,… …   Dictionary of sociology

  • EPA — Environmental Protection Agency (Business » International Business) Environmental Protection Agency (Academic & Science » Meteorology) Environmental Protection Agency (Governmental » Military) Environmental Protection Agency (Academic & Science » …   Abbreviations dictionary

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